Mast cells play what key role in initiating an immune response?

Answers

Answer 1

Mast cell release histamine and heparins molecules that are significant in initiating/mediating the inflammatory response. This is why mast cells are highly granulated and are categorized as granulocytes. An example of such a response is when an allergen bind to the IgE of a mast cell inducing secondary communication mechanism inside the cell leading to release of the transmitters.

Answer 2

Final answer:

Mast cells initiate an immune response by releasing histamine and other inflammatory mediators. They have roles in both promoting and modulating inflammation, particularly in allergic reactions such as asthma and food allergies.

Explanation:

Mast cells play a crucial role in initiating an immune response by detecting injury to nearby cells and releasing histamine, which jump-starts the inflammatory response. These cells contain granules with a plethora of mediators such as eosinophil chemotactic factor, neutrophil chemotactic factor, platelet activating factor, and a range of cytokines including IL-3, IL-4, IL-5, IL-6, and TNF-alpha. They are also involved in synthesizing leukotrienes and prostaglandins that enhance inflammation through mechanisms such as vasodilation, increased capillary permeability, and increased mucous production.

However, beyond being pro-inflammatory, mast cells also exhibit immunomodulatory effects in allergic inflammation. They are seen as troublesome due to their substantial role in IgE-dependent allergic hypersensitivity reactions, like allergic asthma and food allergies. Despite this, recent findings suggest that mast cells can also have suppressive effects that modulate allergic responses, showing their dual nature in the body's reaction to allergens and infections.


Related Questions

Chemical signals in plants affecting the growth, activity, and development of cells and tissues are called

Answers

Hormones

the big five are

ABSCISIC ACID

ETYLENE

CYTOKININ

GIBBERELLIN

AUXIN

For the problem below, translate the fly descriptions into parental genotypes, then continue asinstructed.Consider a cross between female flies homozygous for brown bodies and red eyes and male flieshomozygous for ebony bodies and sepia eyes. Give the genotypes and the possible gametes of eachset of parents.Female Genotype: SSEE Gametes Possible: SE Male Genotype: ssee Gametes Possible: se

Answers

Answer:

Offspring-heterozygous genotype SsEe

Explanation:

If we name the gene  for the body color with S and gene for the eye color with E and if the brown body is dominant over ebony body, while red eyes are dominant over sepia eyes, than the genotypes  of the parents would be: female-SSEE, male-ssee

P: SSEE  x  ssee

Female gametes SE, male gametes se

F1: SsEe all of the offspring would be heterozygous.

Final answer:

A cross between a white-eyed male and a heterozygous red-eyed female will produce offspring where 50% of the males have white eyes and 50% have red eyes and 50% of females are heterozygous for red eyes while the other 50% are homozygous for red eyes.

Explanation:

For a cross between a white-eyed male and a female that is heterozygous for red eye color, the possible genetic outcomes follow X-linked inheritance patterns. As females have two X chromosomes, a heterozygous female with one red-eye allele (XW) and one white-eye allele (Xw) can produce gametes with either allele. A male with white eyes (XwY) can only produce gametes with the white-eye allele on the X chromosome or the Y chromosome without this gene. Thus, 50% of their male offspring are predicted to have white eyes (XwY), inheriting the white-eye allele from either parent, and the other 50% will have red eyes (XWY), inheriting the red-eye allele from their mother and the Y chromosome from their father. Similarly, 50% of their female offspring will be heterozygous for red eye color (XWXw), while the other 50% will be homozygous for red eyes (XWXW) because they inherit the XW from their mother.

Which of the following best describes an example of a specific immune response to pathogens?

Cytotoxic T cells are activated and destroy cells that pathogens have invaded.
Fever increases body temperature and speeds up the body’s reaction to pathogens.
Phagocytes identify cells invaded by pathogens and mark them for destruction.
Mucus traps pathogens and destroys them before they can enter the body.

Answers

Cytotoxic T cells play a crucial role in the body's specific immune response by identifying and destroying cells infected with pathogens, with a few remaining as memory cells for faster response upon re-infection.

The specific immune response to pathogens involves the activation and function of cytotoxic T cells (CTLs). When these cells encounter infected body cells presenting specific pathogen antigens using Major Histocompatibility Complex (MHC) I molecules, they become activated. These activated cytotoxic T cells then use various mechanisms, such as releasing toxins, to destroy the infected cells, thereby containing the spread of the infection. These cells are particularly important when a pathogen has entered a cell, making it invisible to the humoral immune response which deals with pathogens in bodily fluids. The persistence of a few memory cytotoxic T cells after an infection ensures a quicker immune response if the same pathogen re-infects the body in the future.

Active transport requires select one:

a. thermal energy from the environment.

b. the initial movement of water by osmosis to develop a favorable concentration gradient.

c. cellular energy, usually in the form of atp.

d. hormonal activation of specific protein carriers.

Answers

Answer:

C

Explanation:

Active transport is against gradient.. Or uphill movement.. So we have to spend energy.. Which are in the form of ATP(adenosinetriphosphate).

Active transport process require cellular energy to transport substance up their concentration gradients across the plasma membrane. Cellular energy usually in the form of ATP. Thus, c is correct option.

What is active transport?

When movement of molecules is takes place then it is called active transport.

Active transport movement is always from lower concentration to a region of higher concentration gradients. So we can say that  substance are moving their own concentration gradients.

Active transport requires the signal or input of cellular energy in the form of ATP( adenosine triphosphate).

ATP is generally energy carrying molecule which are found in all living organisms. Active transport system are always sensitive to metabolic poisons because these metabolic poisons interrupt the ATP supply.

Therefore, active transport process require cellular energy to transport substance up their concentration gradients across the plasma membrane. Cellular energy usually in the form of ATP. Thus c is correct option.

Learn more about active transport here:

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Primary succession is most likely caused by .

Answers

Primary succession most likely occurs because of a natural disaster

Carbohydrates are nutrients that supply the main energy source for the body. True or false?

Answers

The answer is false on Apex

Both phospholipids and proteins are asymmetrically located in cell membranes - meaning the outer half and the inner half of the bilayer contain different phospholipids and the proteins have a cytoplasmic side and an "out" side. In experiments when detergents are used to disrupt the cell membrane, a water soluble mixture of lipids and proteins is the result. Then, if the detergents are subsequently removed by dialysis, the lipid bilayer will reform spontaneously with the proteins included. Except now the asymmetry is gone and both proteins and lipids are located randomly in the newly formed membrane. What does this result tell you about how the cell synthesizes cellular membranes

Answers

Answer:

The process of cell membrane synthesis is regulated.

Explanation:

The components of cell membrane (lipids, proteins, carbohydrates) are synthesized inside the cell organelles: endoplasmic reticulum and Golgi apparatus. After the synthesis, they are transported via vesicular transport also called vesicular trafficking. The transport is also very regulated process (molecules contain transport signal sequences). Components are secreted from the vesicles via exocytosis, when they arrive to their target location.

During conjugation what is transferred from one bacteria to the next

Answers

Answer:

Genetic material

Explanation:

Conjugation is one of the ways by which bacteria exchange their genetic material (horizontal gene transfer). Two bacterial cells must physically connect in order to perform the conjugation. The linking occurs through a pilus.

Pilus is an appendage on the surface of bacteria cell and it is also called fimbria. Pilus is  filamentous, tubular and composed of oligomeric proteins-pilin.

Donor cell contain pilus that will attach to the recipient bacterial cell and induce the transfer.

Which statement best describes how the evolution of pesticide resistance occurs in a population of insects?A. Individual members of the population slowly adapt to the presence of the chemical by striving to meet the new challengeB. All insects exposed to the insecticide begin to use a formerly silent gene to make a new enzyme that breaks down the insecticide moleculesC. Insects observe the behavior of other insects that survive pesticide application, and adjust their own behaviors to copy those of the survivorsD. A number of genetically resistant pesticide survivors reproduce. The next generation of insects contains more genes from the survivors than it does from susceptible individuals

Answers

Answer:

D. A number of genetically resistant pesticide survivors reproduce. The next generation of insects contains more genes from the survivors than it does from susceptible individuals

Explanation:

Pesticide resistances in a population of insects usually occurs as a consequence of mutation. Individuals that carry the resistance mutation become favourable by natural selection.

Natural selection is evolutionary mechanism which favours traits of an organism that help him survive and reproduce. In the example, above,   resistant insects that survived after the use of pesticide had the favuoruable trait (resistance) by natural selection.

Which process(es) of the water cycle— precipitation, evaporation, condensation, runoff, percolation or transpiration— that might contribute to the addition of pollutants to rivers, lakes, oceans? Why?

Answers

Runoff percipatation contributes to the dirty water because the rain water picks pollutants from the water and than it falls to the earth and than water continues and spreads into the large body of waters

The process of the water cycle that might contribute to the addition of pollutants to rivers, lakes, and oceans is runoff.

Runoff is exactly as it sounds. It is described as when water runs off the land. This water commonly drains towards:

Rivers LakesOceans

and other bodies of water.

Though pollution is present in every part of the water cycle, it is most visible during runoff. During runoff, water travels downhill through the land, eroding the soil and carrying asking anything it finds asking the way, such as garbage. This garbage then end up in the larger bodies of water and contributes to their pollution.

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Prior to the time of Charles Darwin, it was widely believed that all organisms appeared on Earth at the same time and remained unchanged throughout history. Which of these proved to be the biggest influence in the development of this idea? A) scientific data B) religious beliefs C) Mendel's work with pea plants D) Lamarck's idea of acquired characteristics

Answers

The statement "All organisms appeared on Earth at the same time and remained unchanged throughout history." is just a saying, it does not have any scientific evidence.

And in above option,

'A' shows about scienticific data but there is no any science in statement.

'C' shows Mendel's work with pea plant which is a scientific experiment.

'D' shows Lamarck's idea which is also based ob science.

Therefore, the answer is religious beliefs

Answer:B

Explanation:religious beliefs

How are absorption in the digestive tract and reabsorption from the renal tubules similar? (Your answer should concentrate on the molecular level.)

Answers

Answer:

1. Bcoz all glucose absorbed by active transport.

2. Water absorbed by osmosis in both

3. Most of tje ions absorbed by active transport.

4.haromones and enzymes are involved in both.

5. Waste are excreted out.

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